Encube Ethicals Hiring IVPT specialists

IVPT Scientist (M.Sc/M.Pharm) – Dombivli | Encube Ethicals

Encube Ethicals hiring 2 IVPT specialists (M.Sc/M.Pharm) in Dombivli (Palava). 0–3 yrs experience. Apply for IVPT method development roles.

Encube Ethicals is hiring two IVPT specialists for its Dombivli (Palava) facility. If you’re an M.Sc or M.Pharm graduate aiming to specialise in in‑vitro permeation testing (IVPT) and topical formulation bioequivalence, this role offers hands‑on laboratory exposure, method development responsibilities, and opportunity to work in a GLP/GDP‑compliant environment.

Company Overview

Encube Ethicals is a science‑led contract research organisation focused on topical formulation development, in‑vitro testing services, and regulatory support. The firm collaborates with pharmaceutical and cosmeceutical clients to design IVPT studies, validate analytical methods, and prepare regulatory‑grade study reports. Encube places a premium on scientific rigor, data integrity, and adherence to international GLP/GDP norms — making it an ideal workplace for early‑career scientists who want a technical, growth‑oriented role in bioequivalence science.

Job Role & Responsibilities

Role: IVPT Scientist / Analyst (2 positions)

Location: Dombivli (Palava)
Qualification: M.Sc / M.Pharm
Experience: 0–3 years

This is a laboratory‑intensive role centered on method development, validation, and execution of IVPT studies using the Vertical Franz diffusion apparatus. The position blends experimental work with data analysis and report writing. Core responsibilities:

• Lead or support IVPT method development for topical dosage forms (creams, gels, ointments) using the Vertical Franz diffusion apparatus.
• Design and execute pilot and pivotal IVPT studies according to approved protocols, SOPs, and regulatory guidance relevant to in‑vitro bioequivalence (IVBE).
• Handle human cadaver skin responsibly: storage, retrieval, mounting on Franz cells, and maintaining chain‑of‑custody in line with ethical, GLP, and GDP practices.
• Prepare and validate reagents, buffers, and donor/receiver solutions required for IVPT studies.
• Perform accurate calculations of flux, cumulative permeation, and AMT (amount permeated) using MS Excel and, where required, SAS/statistical tools to support bioequivalence conclusions.
• Maintain meticulous raw data records, log books, and electronic workbooks to ensure audit readiness.
• Operate and maintain laboratory equipment: Vertical Franz diffusion cells, micropipettes, handystep dispensers, analytical balances, vapometers, and temperature control systems.
• Conduct in‑house calibration and routine verification for IVPT apparatus and ancillary instruments.
• Prepare technical protocols, validation plans, and comprehensive IVPT reports suitable for internal review and client submissions.
• Communicate study progress, variances, and technical findings to the Group Leader and cross‑functional stakeholders.
• Ensure all activities conform to GLP and GDP standards and support audit preparedness during inspections or client audits.

Why this role is high‑value

IVPT scientists play a critical part in reducing reliance on clinical bioequivalence studies for topical products. Strong IVPT data can support regulatory submissions and speed time‑to‑market while maintaining patient safety. Mastering IVPT method development and Franz cell operation positions you in a niche, high‑demand segment of pharmaceutical analytics — skills valued by CROs, formulation developers, and regulatory affairs teams.

Eligibility / Qualifications

Minimum Education:

• M.Sc (Analytical Chemistry, Pharmaceutical Sciences, Pharmaceutics, Biopharmaceutics) OR M.Pharm.

Experience:

• Fresh M.Sc/M.Pharm graduates with laboratory project experience are welcome.
• Candidates with up to 3 years of relevant IVPT, topical formulation, or analytical lab experience will be prioritised.

Technical skills (preferred):

• Familiarity with Franz diffusion cell methodology and sample handling.
• Hands‑on HPLC or other analytical instrument exposure is advantageous.
• Proficiency in MS Excel for calculations and data handling; basic knowledge of SAS or statistical packages is a plus.
• Solid GLP/GDP documentation practice and experience preparing laboratory reports.

Soft skills:

• Strong attention to detail, methodical record keeping, and clear scientific communication.
• Team player with the ability to take direction and drive experiments to completion.

Relevant courses (comma‑separated):
Pharmaceutics, Pharmaceutical Analysis, Analytical Chemistry, Biopharmaceutics, Skin Biology, Regulatory Affairs, Quality Assurance, Cosmeceuticals, Pharmacokinetics.

Location & Compensation

Work Location: Dombivli (Palava), Mumbai Metropolitan Region
Work Environment: Laboratory (GLP/GDP) with standard safety protocols.
Compensation: Competitive salary/stipend aligned with experience — exact band to be discussed during interview.

Training & Career Progression

Encube Ethicals offers role‑specific training covering IVPT best practices, ethical handling of biological samples, and GLP documentation standards. High performers can progress to Senior Scientist roles, lead IVPT projects, or move into regulatory science and bioequivalence consultancy. The IVPT skill set opens doors to CROs, formulation R&D, and regulatory affairs teams across pharma and cosmetics sectors.

Application Process

Send your updated CV to: pranali.sarvagod@encubeethicals.com
Include a 1‑sentence note mentioning any IVPT, topical formulation, or laboratory project exposure. Shortlisted candidates will be contacted for technical assessments and interviews with the Group Leader (Prashant Ghoge / Amruta Dhuri).

Interview Preparation Checklist

• Bring specific details of any lab projects or thesis work, especially those involving permeation, dissolution, or topical formulations.
• Be ready to explain basic IVPT theory (flux, cumulative permeation, AMT) and metric calculations performed in Excel.
• Expect a practical discussion on GLP/GDP documentation and lab equipment maintenance routines.

FAQs

Q: Are freshers eligible?
A: Yes — the role accepts fresh M.Sc/M.Pharm graduates with relevant lab exposure. Candidates with up to 3 years’ practical experience are preferred.

Q: Do I need prior experience with human cadaver skin?
A: No. Prior exposure is beneficial but not mandatory. Training on ethical handling and procedures will be provided.

Q: Which software will I use for analysis?
A: Daily work relies on MS Excel for calculations. Familiarity with SAS or statistical packages is advantageous for bioequivalence assessments.

Q: Will I be involved in regulatory submissions?
A: You will prepare technical reports and validation documents that feed into regulatory dossiers; senior staff typically handle submission coordination.

Q: What standards govern the work?
A: GLP (Good Laboratory Practice) and GDP (Good Documentation Practice) are core requirements. Adherence to SOPs and ethical sample handling is mandatory.

Summary Table

Category	Details
Company	Encube Ethicals
Vacancies	IVPT Scientist / Analyst (2 positions)
Required Education	M.Sc, M.Pharm (Pharmaceutics, Analytical Chemistry, Pharmaceutical Science)
Experience	0–3 years